Clinical features and outcomes of young patients with epithelioid sarcoma: an analysis from the Children’s Oncology Group (COG) and the European paediatric soft tissue Sarcoma Study Group (EpSSG) prospective clinical trials
Spunt S, Francotte N, De Salvo GL, Chi YY, Zanetti I, Hayes-Jordan A, Kao S, Orbach D, Brennan B, Weiss A, Van Noesel M, Million L, Alaggio R, Parham D, Kelsey A, Randall RL, McCarville MB, Bisogno G, Hawkins D, Ferrari A, EIC Eur J Cancer. 2019 Apr 4;112:98-106. DOI: 10.1016/j.ejca.2019.02.001.
Abstract Background: Data on the clinical features, optimal treatment and outcomes of paediatric…
Outcome of localized liver-bile duct rhabdomyosarcoma according to local therapy. A report from the European paediatric Soft Tissue Sarcoma Study Group (EpSSG)- RMS 2005 study.
Guerin F, Rogers T, Minard-Colin V, Gaze M, Terwisscha S, van Noesel M, De Corti F, Guillen Burrieza G, De Salvo GL, Kelsey A, Orbach D, Ferrari A, Bergeron C, Bisogno G, Martelli H, Pediatr Blood Cancer. 2019 Mar 28:e27725. DOI: 10.1002/pbc.27725
Abstract Objectives To evaluate the impact of local therapies on the outcome of patients with…
Indeterminate pulmonary nodules at diagnosis in pediatric rhabdomyosarcoma: are we undertreating patients? A report from the European paediatric Soft tissue sarcoma Study Group-RMS-2005 protocol.
Vaarwerk B, Bisogno G, McHugh K, Brisse H, Morosi C, Corradini N, Jenney M, Orbach D, Chisholm J, Ferrari A, Zanetti I, De Salvo GL, Van Rijn RR, Merks JHM, EpSSG Radiology Group. J Clin Oncol. 2019 Jan 31:JCO1801535. DOI: 10.1200/JCO.18.01535
Abstract Purpose To evaluate the clinical significance of indeterminate pulmonary nodules at…
Localized vaginal/uterine rhabdomyosarcoma-results of a pooled analysis from four international cooperative groups.
Minard-Colin V, Walterhouse D, Bisogno G, Martelli H, Anderson J, Rodeberg DA, Ferrari A, Jenney M, Wolden S, De Salvo G, Arndt C, Merks JHM, Gallego S, Schwob D, Haie-Meder C, Bergeron C, Stevens MCG, Oberlin O, Hawkins D; International Society of Pediatric Oncology Sarcoma Committee, the Children's Oncology Group, the Italian Cooperative Soft Tissue Sarcoma Group, and the European pediatric Soft tissue sarcoma Study Group. Pediatr Blood Cancer. 2018 Sep;65(9):e27096. DOI: 10.1002/pbc.27096.
Abstract Background Vaginal/uterine rhabdomyosarcoma (VU RMS) is one of the most favorable RMS…
Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results from a Pooled-Analysis of North American and European Cooperative Groups
Walterhouse D, Barkauskas D, Hall D, Ferrari A, De Salvo GL, Koscielniak E, Stevens M, Martelli H, Seitz G, Rodeberg D, Shnorhavorian M, Dasgupta R, Breneman JC, Anderson JR, Bergeron C, Bisogno G, Meyer WH, Hawkins D, Minard-Colin V. J Clin Oncol. 2018 Oct 23:JCO2018789388. DOI: 10.1200/JCO.2018.78.9388.
Purpose Treatment recommendations for localized paratesticular rhabdomyosarcoma (PT RMS) differ in…
Fusion status in node-positive (n1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: the experience of the European paediatric soft tissue Sarcoma Study Group (EpSSG)
Gallego Melcón S, Zanetti I, Orbach D, Ranchère D, Shipley J, Zin A, Bergeron C, De Salvo GL, Chisholm J, Ferrari A, Jenney M, Mandeville HC, Rogers T, Merks JH, Mudry P, Glosli H, Milano GM, Ferman S, Bisogno G, on behalf of the EpSSG (European Paediatric Soft Tissue Sarcoma Study Group), Fusion status in node-positive (n1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: the experience of the European paediatric soft tissue Sarcoma Study Group (EpSSG). Cancer. 2018. DOI: 10.1002/cncr.31553.
Abstract BACKGROUND Alveolar rhabdomyosarcoma (aRMS) with lymph node involvement (N1 classification)…
The Addition of dose-intensified doxorubicin to standard chemotherapy for rhabdomyosarcoma (EpSSG RMS 2005): a multicenter, open-label, randomized controlled, phase 3 trial
Bisogno G, Jenney M, Bergeron C, Gallego Melcón S, Ferrari A, Oberlin O, Carli M, Stevens M, Kelsey A, De Paoli A, Gaze MN, Martelli H, Devalck C, Merks JH, Ben-Arush M, Glosli H, Chisholm J, Orbach D, Minard-Colin V, De Salvo GL, for the EpSSG. The Addition of dose-intensified doxorubicin to standard chemotherapy for rhabdomyosarcoma (EpSSG RMS 2005): a multicenter, open-label, randomized controlled, phase 3 trial. Lancet Oncol. 2018. pii: S1470-2045(18)30337-1. DOI: 10.1016/S1470-2045(18)30337-1
Abstract Background: Rhabdomyosarcoma is an aggressive tumour that can develop in almost any part of…
Genomic complexity in pediatric synovial sarcomas (SYNOBIO study): the European Pediatric Soft tissue Sarcoma Group (EpSSG) experience
Orbach D, Mosseri V, Pissaloux D, Pierron G, Brennan B, Ferrari A, Chibon F, Bisogno G, De Salvo GL, Chakiba C, MD, Corradini N, Minard-Colin V, Kelsey A,Ranchère-Vince D. Genomic complexity in pediatric synovial sarcomas (SYNOBIO study): the European Pediatric Soft tissue Sarcoma Group (EpSSG) experience. Cancer Medicine. 2017. DOI: 10.1002/cam4.1415
Abstract A genomic index (GI) tool using array comparative genomic hybridization (aCGH) on tumor…
Alveolar Soft Part Sarcoma in children and adolescents: the European Paediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005)
Brennan B, Zanetti I, Orbach D, Gallego S, Francotte N, Van Noesel M, Kelsey A, Casanova M, De Salvo GL, Bisogno G, Ferrari A. Alveolar Soft Part Sarcoma in children and adolescents: the European Paediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005). Pediatr Blood Cancer. 2017 e26942. DOI:101002/pbc.26942
Abstract Background As alveolar soft part sarcomas (ASPS) are rare with no prospective series within…
Paratesticular rhabdomyosarcoma in children and adolescents-Outcome and patterns of relapse when utilizing a nonsurgical strategy for lymph node staging: Report from the International Society of Paediatric Oncology (SIOP) Malignant Mesenchymal Tumour 89 and 95 studies.
Rogers T, Minard-Colin V, Cozic N, Jenney M, Merks JHM, Gallego S, Devalck C, Gaze MN, Kelsey A, Oberlin O, Stevens M, Spicer RD, Bergeron C, Martelli H.
Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26486. Epub 2017 Feb 16.
Abstract Purpose: To report the results from International Society of Pediatric Oncology (SIOP)…
Open-label, multicentre, randomised, phase II study of the EpSSG and the ITCC evaluating the addition of bevacizumab to chemotherapy in childhood and adolescent patients with metastatic soft tissue sarcoma (the BERNIE study)
Chisholm J, Merks JHM, Casanova M, Bisogno G, Orbach D, Gentet JC, Thomassin-Defachelles A, Chastagner P, Lowis S, Ronghe M, McHugh K, van Rijn RR, Hilton M, Bachir J, Furst-Recktenwald S, Geoerger B, Oberlin O. Open-label, multicentre, randomised, phase II study of the EpSSG and the ITCC evaluating the addition of bevacizumab to chemotherapy in childhood and adolescent patients with metastatic soft tissue sarcoma (the BERNIE study). Eur J of Cancer. 2017 Sept 83:177-184. DOI: 10.1016/j.ejca.2017.06.015
Abstract Purpose: We evaluated the role of bevacizumab as part of the multi-modality treatment of…
The EpSSG NRSTS 2005 treatment protocol for desmoid-type fibromatosis in children: an international prospective case series
Orbach D, Brennan B, Bisogno G, Van Noesel M, Minard-Colin V, Daragjati J, Casanova M, Corradini N, Zanetti I, De Salvo GL, Defachelles AS, Kelsey A, Ben Arush M, Francotte N, Ferrari A. The EpSSG NRSTS 2005 treatment protocol for desmoid-type fibromatosis in children: an international prospective case series. The Lancet child-adol. 2017 Sept DOI:org/10.1016/S2352-4642(17)30045-7
Background In 2005, the European Pediatric Soft Tissue Sarcoma Study Group (EpSSG) proposed a…
Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group
Ferrari A, Chi YY, De Salvo GL, Orbach D, Brennan B, Randall RL, McCarville MB, Black JO, Alaggio R, Hawkins DS, Bisogno G, Spunt SL. Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group. Eur J Cancer. 2017 Apr 6;78:1-6. DOI: 10.1016/j.ejca.2017.03.003
Abstract Background: Multimodal risk-adapted treatment is used in paediatric protocols for synovial…
Access to clinical trials for adolescents with Soft tissue sarcomas: enrollment in European pediatric Soft tissue sarcoma Study Group (EpSSG) protocols
Ferrari A, Trama, De Paoli, Bergeron, Merks, Jenney, Orbach, Chisholm, Gallego, Glosli, De Salvo, Botta, Gatta, Bisogno. Access to clinical trials for adolescents with Soft tissue sarcomas: enrollment in European pediatric Soft tissue sarcoma Study Group (EpSSG) protocols. Pediatr Blood Cancer. 2017 Jun;64(6). DOI: 10.1002/pbc.26348
Abstract Background Adolescents with cancer are enrolled in clinical trials at far lower rates than…
Outcome of extracranial malignant rhabdoid tumours in children registered in the European Paediatric Soft Tissue Sarcoma Study Group Non-Rhabdomyosarcoma Soft Tissue Sarcoma 2005 Study-EpSSG NRSTS 2005
Brennan B, De Salvo GL, Orbach D, De Paoli A, Kelsey A, Mudry P, Francotte N, Van Noesel M, Bisogno G, Casanova M, Ferrari A. Outcome of extracranial malignant rhabdoid tumours in children registered in the European Paediatric Soft Tissue Sarcoma Study Group Non-Rhabdomyosarcoma Soft Tissue Sarcoma 2005 Study-EpSSG NRSTS 2005. Eur J Cancer. 2016 Jun;60:69-82. DOI: 10.1016/j.ejca.2016.02.027
Abstract Background: Extracranial malignant rhabdoid tumours (MRT) are rare lethal childhood cancers…
Conservative strategy in infantile fibrosarcoma is possible: The European paediatric Soft tissue sarcoma Study Group experience
Orbach D, Brennan B, De Paoli A, Gallego S, Mudry P, Francotte N, van Noesel M, Kelsey A, Alaggio R, Ranchère D, De Salvo GL, Casanova M, Bergeron C, Merks, JH, Jenney M, Stevens MC, Bisogno G, Ferrari A. Conservative strategy in infantile fibrosarcoma is possible: The European paediatric Soft tissue sarcoma Study Group experience. Eur J Cancer. 2016 Apr;57:1-9. DOI: 10.1016/j.ejca.2015.12.028
Abstract Background Infantile fibrosarcoma (IFS) is a very rare disease occurring in young infants…
Synovial sarcoma in children and adolescents: the European Pediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005)
Ferrari A, De Salvo GL, Brennan B, van Noesel MM, De Paoli A, Casanova M, Francotte N, Kelsey A, Alaggio R, Oberlin O, Carli M, Ben-Arush M, Bergeron C, Merks JH, Jenney M, Stevens MC, Bisogno G, Orbach D. Synovial sarcoma in children and adolescents: the European Pediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005). Ann Oncol. 2015 Mar;26(3):567-72. DOI: 10.1093/annonc/mdu562
Abstract Background: To report the results of the first European prospective nonrandomized trial…
