Metastatic Rhabdomyosarcoma: Results of the European Paediatric Soft Tissue Sarcoma Study Group MTS 2008 Study and Pooled Analysis With the Concurrent BERNIE Study.
Schoot RA, Chisholm JC, Casanova M, Minard-Colin V, Geoerger B, Cameron AL, Coppadoro B, Zanetti I, Orbach D, Kelsey A, Rogers T, Guizani C, Elze M, Ben-Arush M, McHugh K, van Rijn RR, Ferman S, Gallego S, Ferrari A, Jenney M, Bisogno G, Merks JHM J Clin Oncol. 2022 Jun 16:JCO2102981. doi: 10.1200/JCO.21.02981. Online ahead of print.PMID: 35709412
Abstract Purpose: Outcome for patients with metastatic rhabdomyosarcoma (RMS) is poor. This study…
Adolescents and young adults with rhabdomyosarcoma treated in the European paediatric Soft tissue sarcoma Study Group (EpSSG) protocols: a cohort study.
Ferrari A, Chisholm J, Jenney M, Minard-Colin V, Orbach D, Casanova M, Guillen G, Glosli H, van Rijn RR, Schoot RA, Cameron AL, Rogers T, Alaggio R, Ben-Arush M, Mandeville HC, Devalck C, Defachelles AS, Coppadoro B, Bisogno G, Merks JHM. Lancet Child Adolesc Health. 2022 Jun 8;S2352-4642(22)00121-3. doi: 10.1016/S2352-4642(22)00121-3. Online ahead of print.
Abstract Background: Adolescent and young adult patients with rhabdomyosarcoma often have poorer…
Perianal/perineal rhabdomyosarcoma: results of the SIOP MMT-95, ITALIAN RMS-96, and EpSSG RMS-2005 studies
Rogers T, Zanetti I, Coppadoro B, Martelli H, Jenney M, Minard-Colin V, Terwisscha van Scheltinga SEJ, Skerritt C, Dávila Fajardo R, Guérin F, Kelsey A, Merks JHM, Mandeville H, Guillén G, Glosli H, Bisogno G. Pediatr Blood Cancer 2022 Apr 23;e29739. doi: 10.1002/pbc.29739. Online ahead of print.
Abstract Background/objectives: Rhabdomyosarcoma of the perianal/perineal region (PRMS) is rare,…
In transit metastases in children, adolescents and young adults with localized rhabdomyosarcoma of the distal extremities: Analysis of the EpSSG RMS 2005 study.
Terwisscha van Scheltinga CEJ, Wijnen MHWA, Martelli H, Guerin F, Rogers T, Craigie RJ, Guillén Burrieza G, Dall'Igna P, De Corti F, Smeulders N, van Rijn RR, Dávila Fajardo R, Mandeville HC, Zanetti I, Coppadoro B, Minard-Colin V, Jenney M, Bisogno G, van Noesel MM, van der Steeg AFW, Merks JHM. European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology Follow journal, doi: 10.1016/j.ejso.2022.03.001
Abstract In-transit metastases (ITM) are defined as metastatic lymph nodes or deposits occurring…
Localised rhabdomyosarcoma in infants (< 12 months) and young children (12-36 months of age) treated on the EpSSG RMS 2005 study
Slater O, Gains J, Kelsey A, De Corti F, Zanetti I, Coppadoro B, Jorgensen M, Gallego S, Orbach D, Glosli H, Cesen M, Gaze MN, Smeulders N, Ferrari A, Jenney M, Minard-Colin V, Bisogno G, .Merks JHM for the European paediatric Soft tissue sarcoma Study Group Eur J Cancer. 2022 Jan;160:206-214. doi: 10.1016/j.ejca.2021.10.031. Epub 2021 Dec 2.
Abstract Background: Infants (<12 months) with rhabdomyosarcoma have historically had poorer outcome…
Congenital rhabdomyosarcoma: A report from the European paediatric Soft tissue sarcoma Study Group
Bisogno G, Minard-Colin V, Arush MB, Daragjati J, Coppadoro B, Gallego S, Alaggio R, Smeulders N, Mudry P, Zin A, Merks JHM, Slater O. Pediatr Blood Cancer. 2021 Sep 28:e29376. doi: 10.1002/pbc.29376.
Abstract Procedure Congenital rhabdomyosarcoma (RMS) represents a challenging disease due to its…
Role of 18F-FDG-PET/CT in the staging of metastatic rhabdomyosarcoma: a report from the European paediatric Soft tissue sarcoma Study Group.
Mercolini F, Zucchetta P, Jehanno N, Corradini N, Van Rijn RR, Rogers T, Cameron A, Scarzello G, Coppadoro B, Minard-Colin V, Gallego S, Chisholm J, Merks JH, Bisogno G Eur J Cancer. 2021 Aug 9;155:155-162. doi: 10.1016/j.ejca.2021.07.006. Online ahead of print.
Abstract Background: Initial staging of rhabdomyosarcoma is crucial for prognosis and to tailor the…
Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft tissue Sarcoma Study Group and Innovative Therapies for Children With Cancer Trial.
Defachelles AS, Bogart E, Casanova M, Merks JHM, Bisogno G, Calareso G, Gallego Melcon S, Gatz SA, Le Deley MC, McHugh K, Probst A, Rocourt N, van Rijn RR, Wheatley K, Minard-Colin V, Chisholm JC. J Clin Oncol. 2021 Aug 3:JCO2100124. doi: 10.1200/JCO.21.00124. Online ahead of print.PMID: 34343032
Abstract Purpose: The VIT-0910 trial was conducted to evaluate efficacy and safety of the…
The Impact of Radiation Therapy in Children and Adolescents With Metastatic Rhabdomyosarcoma.
Cameron AL, Elze MC, Casanova M, Geoerger B, Gaze MN, Minard-Colin V, McHugh K, van Rijn RR, Kelsey A, Martelli H, Mandeville H, Bisogno G, Lowis S, Ronghe M, Orbach D, Guizani C, Fürst-Recktenwald S, Chisholm JC, Merks JHM,European Paediatric Soft Tissue Sarcoma Study Group (EpSSG) and the European Innovative Therapies for Children with Cancer (ITCC) Consortium. Int J Radiat Oncol Biol Phys. 2021 Jul 1:S0360-3016(21)00823-3. doi: 10.1016/j.ijrobp.2021.06.031. Online ahead of print.
Abstract Purpose: There is limited evidence to define the role of radiation therapy in children with…
Paediatric non-rhabdomyosarcoma soft tissue sarcomas: the prospective NRSTS 2005 study by the European Pediatric Soft Tissue Sarcoma Study Group (EpSSG)
Ferrari A, van Noesel M, Brennan B, Zanetti I, Casanova M, Berlanga P, Merks JHM, Alaggio R, Schifflers S, Ramirez Vilar G, Giraudo C, Guillén Burrieza G, Safwat A, Bisogno G, De Salvo
GL, Orbach D The Lancet Child & Adolescent Health June 2021, doi: 10.1016/S2352-4642(21)00159-0
Summary Background A standardised approach to treatment of paediatric non-rhabdomyosarcoma soft…
Non-parameningeal head and neck rhabdomyosarcoma in children, adolescents, and young adults: Experience of the European paediatric Soft tissue sarcoma Study Group (EpSSG) - RMS2005 study
Glosli H, Bisogno G, Kelsey A, Chisholm J, Gaze M, Kolb F, McHugh K, Shipley J, Gallego S, Merks JHM, Smeele LE, Mandeville H, Ferrari A, Minard-Colin V, Corradini N, Jenney M, Zanetti I, De Salvo GL, Orbach D, EpSSG members Eur J Cancer 2021 Jul;151:84-93. doi: 10.1016/j.ejca.2021.04.007. Epub 2021 May 7.
Background/objectives: The primary aim of this study was to analyse and evaluate the impact of…
Pathology of childhood rhabdomyosarcoma: A consensus opinion document from the Children's Oncology Group, European Paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
Rudzinski ER, Kelsey A, Vokuhl C, Linardic CM, Shipley J, Hettmer S, Koscielniak E, Hawkins DS, Bisogno G. Pediatr Blood Cancer. 2021 Mar;68(3):e28798. doi: 10.1002/pbc.28798.
Abstract The diagnosis and classification of rhabdomyosarcoma (RMS) has undergone several shifts…
Embryonal rhabdomyosarcoma completely resected at diagnosis: The European paediatric Soft tissue sarcoma Study Group RMS2005 experience
Bergeron C, Jenney M, De Corti F, Gallego S, Merks JHM, Glosli H, Ferrari A, Ranchère-Vince D, De Salvo GL, Zanetti I, Chisholm J, Minard-Colin V, Rogers T, Bisogno G. on behalf of the European paediatric Soft tissue sarcoma Study Group (EpSSG). European Journal of Cancer, Vol 146, March 2021, 21-29. https://doi.org/10.1016/j.ejca.2020.12.025
Abstract Background Rhabdomyosarcoma (RMS) is the most common form of soft tissue sarcoma in…
Alveolar rhabdomyosarcoma with regional nodal involvement: Results of a combined analysis from two cooperative groups.
Gallego S, Chin YY, Zanetti I, Li M, Merks JHM, Rodeberg DA, van Scheltinga ST, Mascarenhas L, Orbach D, Jenney M, Million L, Minard-Colin V, Wolden S, De Salvo GL, Parham D, Mandeville H, Venkatramani R, Bisogno G, Hawkins DS. Pediatr Blood Cancer. 2020 Nov 27; e28832. doi: 10.1002/pbc.28832.
Abstract Background: Treatment of children and adolescents with alveolar rhabdomyosarcoma (ARMS) and…
Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG-RMS2005 study
Terwisscha van Scheltinga S, Marc H. W. A. Wijnen MHWA, Martelli H, Rogers T, Mandeville H, Gaze MN, McHugh K, Corradini N, Orbach D, Jenney M, Kelsey A, Chisholm J, Gallego S, Glosli H, Ferrari A, Zanetti I, De Salvo GL, Minard-Colin V, Bisogno G, van Noesel M, Merks JHM. Cancer Med. 2020 Oct;9(20):7580-7589. doi: 10.1002/cam4.3365.
Abstract Rhabdomyosarcoma of the extremities present with two main challenges: correct evaluation of…
Surgical Management of Extremity Rhabdomyosarcoma: A Consensus Opinion from the Children’s Oncology Group, European Pediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe
Morris CD, Tunn P, Rodeberg DA, van Scheltinga ST, Binitie O, Godzinski J, Dall'Igna P, Million L, Hawkins DS, Koscielniak E, Bisogno G, Rogers T. Pediatr Blood Cancer 2020 Aug 9;e28608. doi: 10.1002/pbc.28608.
Abstract The treatment of extremity rhabdomyosarcoma remains a challenge due to several adverse…
Paratesticular rhabdomyosarcoma-Impact of Locoregional Approach on Patient Outcome: A Report From the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)
Rogers T, De Corti F, Guillén Burrieza G, Guérin F, van Scheltinga ST, Smeulders N, Craigie R, Jenney M, Kelsey A, Zanetti I, Coppadoro B, De Salvo GL, Bisogno G, Martelli H. Pediatr Blood Cancer. 2020 Jun 23:e28479. doi: 10.1002/pbc.28479.
Abstract Background: Paratesticular rhabdomyosarcoma (PT RMS) is rare compared to benign scrotal…
Spotlight on the treatment of infantile fibrosarcoma in the era of neutrophic tropomyosin receptor kinase inhibitors: International consensus and remaining controversies.
Orbach D, Sparber-Sauer M, Laetsch TW, Minard-Colin V, Bielack SS, Casanova M, Corradini N, Koscielniak E, Scheer M, Hettmer S, Bisogno G, Hawkins D, Ferrari A. EJC of Cancer 137 (2020) 183-192.
Abstract Targeted neurotrophic tropomyosin receptor kinase (TRK) inhibitors offer a highly specific…
Dermatofibrosarcoma Protuberans in children and adolescents: the European Paediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005)
Brennan B, Zanetti I, De Salvo GL, Orbach D, Gallego S, Francotte N, Schifflers S, van Noesel M, Kelsey A, Casanova M, Dagrada GP, Collini P, Zin A, Santoro L, Ferrari A. Pediatr Blood Cancer. 2020 Jun 18;e28351. doi: 10.1002/pbc.28351
Abstract Background As dermatofibrosarcoma protuberans (DFSP) are rare with no prospective series…
Outcomes of metastatic non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) treated within the BERNIE study: a randomised, phase II study evaluating the addition of bevacizumab to chemotherapy.
Ferrari A, Merks JHM, Chisholm JC, Orbach D, Brennan B, Gallego S, van Noesel MM, McHugh K, van Rijn RR, Gaze MN, Martelli H, Bergeron C, Corradini N, Minard-Colin V, Bisogno G, Geoerger B, Caron HN, De Salvo GL, Casanova M. Eur J Cancer. 2020 Mar 13;130:72-80. doi: 10.1016/j.ejca.2020.01.029.
Abstract Purpose: We analysed the cohort of paediatric patients with metastatic non-rhabdomyosarcoma…
