Publications

Congenital rhabdomyosarcoma: A report from the European paediatric Soft tissue sarcoma Study Group

Bisogno G, Minard-Colin V, Arush MB, Daragjati J, Coppadoro B, Gallego S, Alaggio R, Smeulders N, Mudry P, Zin A, Merks JHM, Slater O. Pediatr Blood Cancer. 2021 Sep 28:e29376. doi: 10.1002/pbc.29376.

Abstract Procedure Congenital rhabdomyosarcoma (RMS) represents a challenging disease due to its…

Role of 18F-FDG-PET/CT in the staging of metastatic rhabdomyosarcoma: a report from the European paediatric Soft tissue sarcoma Study Group.

Mercolini F, Zucchetta P, Jehanno N, Corradini N, Van Rijn RR, Rogers T, Cameron A, Scarzello G, Coppadoro B, Minard-Colin V, Gallego S, Chisholm J, Merks JH, Bisogno G Eur J Cancer. 2021 Aug 9;155:155-162. doi: 10.1016/j.ejca.2021.07.006. Online ahead of print.

Abstract Background: Initial staging of rhabdomyosarcoma is crucial for prognosis and to tailor the…

Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft tissue Sarcoma Study Group and Innovative Therapies for Children With Cancer Trial.

Defachelles AS, Bogart E, Casanova M, Merks JHM, Bisogno G, Calareso G, Gallego Melcon S, Gatz SA, Le Deley MC, McHugh K, Probst A, Rocourt N, van Rijn RR, Wheatley K, Minard-Colin V, Chisholm JC. J Clin Oncol. 2021 Aug 3:JCO2100124. doi: 10.1200/JCO.21.00124. Online ahead of print.PMID: 34343032

Abstract Purpose: The VIT-0910 trial was conducted to evaluate efficacy and safety of the…

The Impact of Radiation Therapy in Children and Adolescents With Metastatic Rhabdomyosarcoma.

Cameron AL, Elze MC, Casanova M, Geoerger B, Gaze MN, Minard-Colin V, McHugh K, van Rijn RR, Kelsey A, Martelli H, Mandeville H, Bisogno G, Lowis S, Ronghe M, Orbach D, Guizani C, Fürst-Recktenwald S, Chisholm JC, Merks JHM,European Paediatric Soft Tissue Sarcoma Study Group (EpSSG) and the European Innovative Therapies for Children with Cancer (ITCC) Consortium. Int J Radiat Oncol Biol Phys. 2021 Jul 1:S0360-3016(21)00823-3. doi: 10.1016/j.ijrobp.2021.06.031. Online ahead of print.

Abstract Purpose: There is limited evidence to define the role of radiation therapy in children with…

Paediatric non-rhabdomyosarcoma soft tissue sarcomas: the prospective NRSTS 2005 study by the European Pediatric Soft Tissue Sarcoma Study Group (EpSSG)

Ferrari A, van Noesel M, Brennan B, Zanetti I, Casanova M, Berlanga P, Merks JHM, Alaggio R, Schifflers S, Ramirez Vilar G, Giraudo C, Guillén Burrieza G, Safwat A, Bisogno G, De Salvo
GL, Orbach D The Lancet Child & Adolescent Health June 2021, doi: 10.1016/S2352-4642(21)00159-0

Summary Background A standardised approach to treatment of paediatric non-rhabdomyosarcoma soft…

Non-parameningeal head and neck rhabdomyosarcoma in children, adolescents, and young adults: Experience of the European paediatric Soft tissue sarcoma Study Group (EpSSG) - RMS2005 study

Glosli H, Bisogno G, Kelsey A, Chisholm J, Gaze M, Kolb F, McHugh K, Shipley J, Gallego S, Merks JHM, Smeele LE, Mandeville H, Ferrari A, Minard-Colin V, Corradini N, Jenney M, Zanetti I, De Salvo GL, Orbach D, EpSSG members Eur J Cancer 2021 Jul;151:84-93. doi: 10.1016/j.ejca.2021.04.007. Epub 2021 May 7.

Background/objectives: The primary aim of this study was to analyse and evaluate the impact of…

Pathology of childhood rhabdomyosarcoma: A consensus opinion document from the Children's Oncology Group, European Paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.

Rudzinski ER, Kelsey A, Vokuhl C, Linardic CM, Shipley J, Hettmer S, Koscielniak E, Hawkins DS, Bisogno G. Pediatr Blood Cancer. 2021 Mar;68(3):e28798. doi: 10.1002/pbc.28798.

Abstract The diagnosis and classification of rhabdomyosarcoma (RMS) has undergone several shifts…

Embryonal rhabdomyosarcoma completely resected at diagnosis: The European paediatric Soft tissue sarcoma Study Group RMS2005 experience

Bergeron C, Jenney M, De Corti F, Gallego S, Merks JHM, Glosli H, Ferrari A, Ranchère-Vince D, De Salvo GL, Zanetti I, Chisholm J, Minard-Colin V, Rogers T, Bisogno G. on behalf of the European paediatric Soft tissue sarcoma Study Group (EpSSG). European Journal of Cancer, Vol 146, March 2021, 21-29. https://doi.org/10.1016/j.ejca.2020.12.025

Abstract Background Rhabdomyosarcoma (RMS) is the most common form of soft tissue sarcoma in…

Alveolar rhabdomyosarcoma with regional nodal involvement: Results of a combined analysis from two cooperative groups.

Gallego S, Chin YY, Zanetti I, Li M, Merks JHM, Rodeberg DA, van Scheltinga ST, Mascarenhas L, Orbach D, Jenney M, Million L, Minard-Colin V, Wolden S, De Salvo GL, Parham D, Mandeville H, Venkatramani R, Bisogno G, Hawkins DS. Pediatr Blood Cancer. 2020 Nov 27; e28832. doi: 10.1002/pbc.28832.

Abstract Background: Treatment of children and adolescents with alveolar rhabdomyosarcoma (ARMS) and…

Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG-RMS2005 study

Terwisscha van Scheltinga S, Marc H. W. A. Wijnen MHWA, Martelli H, Rogers T, Mandeville H, Gaze MN, McHugh K, Corradini N, Orbach D, Jenney M, Kelsey A, Chisholm J, Gallego S, Glosli H, Ferrari A, Zanetti I, De Salvo GL, Minard-Colin V, Bisogno G, van Noesel M, Merks JHM. Cancer Med. 2020 Oct;9(20):7580-7589. doi: 10.1002/cam4.3365.

Abstract Rhabdomyosarcoma of the extremities present with two main challenges: correct evaluation of…

Surgical Management of Extremity Rhabdomyosarcoma: A Consensus Opinion from the Children’s Oncology Group, European Pediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe

Morris CD, Tunn P, Rodeberg DA, van Scheltinga ST, Binitie O, Godzinski J, Dall'Igna P, Million L, Hawkins DS, Koscielniak E, Bisogno G, Rogers T. Pediatr Blood Cancer 2020 Aug 9;e28608. doi: 10.1002/pbc.28608.

Abstract The treatment of extremity rhabdomyosarcoma remains a challenge due to several adverse…

Paratesticular rhabdomyosarcoma-Impact of Locoregional Approach on Patient Outcome: A Report From the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

Rogers T, De Corti F, Guillén Burrieza G, Guérin F, van Scheltinga ST, Smeulders N, Craigie R, Jenney M, Kelsey A, Zanetti I, Coppadoro B, De Salvo GL, Bisogno G, Martelli H. Pediatr Blood Cancer. 2020 Jun 23:e28479. doi: 10.1002/pbc.28479.

Abstract Background: Paratesticular rhabdomyosarcoma (PT RMS) is rare compared to benign scrotal…

Spotlight on the treatment of infantile fibrosarcoma in the era of neutrophic tropomyosin receptor kinase inhibitors: International consensus and remaining controversies.

Orbach D, Sparber-Sauer M, Laetsch TW, Minard-Colin V, Bielack SS, Casanova M, Corradini N, Koscielniak E, Scheer M, Hettmer S, Bisogno G, Hawkins D, Ferrari A. EJC of Cancer 137 (2020) 183-192.

Abstract Targeted neurotrophic tropomyosin receptor kinase (TRK) inhibitors offer a highly specific…

Dermatofibrosarcoma Protuberans in children and adolescents: the European Paediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005)

Brennan B, Zanetti I, De Salvo GL, Orbach D, Gallego S, Francotte N, Schifflers S, van Noesel M, Kelsey A, Casanova M, Dagrada GP, Collini P, Zin A, Santoro L, Ferrari A. Pediatr Blood Cancer. 2020 Jun 18;e28351. doi: 10.1002/pbc.28351

Abstract Background As dermatofibrosarcoma protuberans (DFSP) are rare with no prospective series…

Outcomes of metastatic non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) treated within the BERNIE study: a randomised, phase II study evaluating the addition of bevacizumab to chemotherapy.

Ferrari A, Merks JHM, Chisholm JC, Orbach D, Brennan B, Gallego S, van Noesel MM, McHugh K, van Rijn RR, Gaze MN, Martelli H, Bergeron C, Corradini N, Minard-Colin V, Bisogno G, Geoerger B, Caron HN, De Salvo GL, Casanova M. Eur J Cancer. 2020 Mar 13;130:72-80. doi: 10.1016/j.ejca.2020.01.029.

Abstract Purpose: We analysed the cohort of paediatric patients with metastatic non-rhabdomyosarcoma…

A new standard of care for patients with high-risk rhabdomyosarcoma?

Bisogno G, Ferrari F, Gallego Melcon S, De Salvo GL, Bergeron C, Jenney M. The Lancet Oncol, Correspondence letter, Vol 21 Jan 2020

Inflammatory myofibroblastic tumor: The experience of the European pediatric Soft Tissue Sarcoma Study Group (EpSSG).

Casanova M, Brennan B, Alaggio R, Kelsey A, Orbach D, van Noesel MM, Corradini N, Minard-Colin V, Zanetti I, Bisogno G, Gallego S, Merks JHM, De Salvo GL, Ferrari A. Eur J Cancer. 2020 Jan 30;127:123-129. doi: 10.1016/j.ejca.2019.12.021.

Abstract Introduction: We report the clinical findings and results of treatment in the cohort of…

Is surveillance imaging in pediatric patients treated for localized rhabdomyosarcoma useful? The European experience.

Vaarwerk B, Mallebranche C, Affinita MC, van der Lee JH, Ferrari A, Chisholm JC, Defachelles AS, De Salvo GL, Corradini N, Minard-Colin V, Morosi C, Brisse HJ, McHugh K, Bisogno G, van Rijn RR, Orbach D, Merks JHM, Cancer. 2019 Nov 21. doi: 10.1002/cncr.32603.

Abstract Background After the completion of therapy, patients with localized rhabdomyosarcoma (RMS)…

Vinorelbine and continuous low-dose cyclophosphamide as maintenance chemotherapy in patients with high risk rhabdomyosarcoma (RMS 2005): a multicentre, open label, randomized phase 3 trial.

Bisogno G, De Salvo GL, Bergeron C, Gallego S, Merks JHM, Kelsey A, Martelli H, Minard-Colin V, Orbach D, Glosli H, Chisholm J, Casanova M, Zanetti I, Devalck C, Ben Arush M, Mudry P, Ferman S, Jenney M, Ferrari A. Lancet Oncol. 2019 Sept 24. https://doi.org/S1470-2045(19)30617-5.

Abstract Background: For more than three decades, standard treatment for rhabdomyosarcoma in Europe…

Outcome and prognostic factors in pediatric malignant peripheral nerve sheath tumors: An analysis of the European Pediatric Soft Tissue Sarcoma Group (EpSSG) NRSTS‐2005 prospective study

Van Noesel MM, Orbach D, Brennan B, Kelsey A, Zanetti I, De Salvo GL, Gaze MN, Craigie RJ, McHugh K, Francotte N, Collini P, Bisogno G, Casanova M, Ferrari A. Pediatr Blood Cancer. 2019 Jun 26:e27833. doi: 10.1002/pbc.27833. [Epub ahead of print]

Abstract Background Malignant peripheral nerve sheath tumors (MPNST) are rare tumors of childhood.…